Living life with vigour
Sirtuins are what we like to call the “MacGyvers” of enzymes. They help organisms to streamline their metabolism so that they can withstand adverse conditions. But what does this enzyme family actually have to do with our internal energy supply? And how can we activate these enzymes?
What are sirtuins?
Sirtuins are enzymes that exist naturally in a multitude of plants and animals, including humans, where they regulate body systems and metabolic processes. Through active metabolic intervention, they make it possible for our bodies to withstand adverse conditions such as stress, aging, and mood.
What do sirtuins do?
The dynamic nature of sirtuins increases the chance of surviving certain crisis situations, such as extreme heat, dehydration, or long periods of hunger. Sirtuins set the body’s metabolic processes to “survival mode.” For example, let’s take a cave dweller, whose metabolism effectively switches to “slow mode” when food is scarce. He would clearly have better odds of overcoming hunger than most modern humans, whose metabolism constantly demands food.
How can we benefit from Sirtuins?
For those of us who are not exposed to life-threatening environmental conditions, sirtuins still play a vital role in our wellbeing. Sirtuins are also associated with cell regeneration and the human aging process. These enzymes are closely related to the functions of the vitamin niacin, which supports the energy yield in our endogenous cellular powerhouses (mitochondria), contributing to normal energy metabolism.
In other words, sirtuins control and regulate our body’s machinations, helping us to live our lives to the fullest.
What is Sirtfood?
It was just recently discovered that sirtuins are not only activated in extreme situations, but also by certain foods. Sirtfoods contain a particularly high proportion of particular substances that stimulate the sirtuins already present in your body. Some of the better-known sirtfoods include broccoli, curcuma, and green tea.
The vitamin niacin is also known to stimulate sirtuins. Plant substances such as quercetin (a bioflavonoid), resveratrol (a stilbenoid commonly found in grapes), and its chemical relatives, pterostilbenes, are also closely associated with sirtuin activity. When following the sirtfood diet, you don’t have to starve to activate your endogenous sirtuins, you simply need to eat the right foods. The best part is, you can continue to enjoy things like chocolate and red wine in moderation.
Nutritional supplements containing niacin can also influence sirtuin activity and help you to survive life’s surprises with plenty of energy to spare.
- Goggins, A., Matten, G. 2017. Die Sirtuin Diät – Jung und schlank mit Genuss: So verlieren Sie über 3 Kilo in 7 Tagen
[The Sirtuin Diet – young and slim with enjoyment: how to lose over 3 kg in 7 days]. Goldmann-Verlag, 320 pages.
- Kleine-Gunk, B. et al. 2017. Abnehmen mit SIRTFOOD: Gesünder essen und besser leben mit dem Schutzenzym Sirtuin
[Lose weight with SIRTFOOD: eat healthier and live better with the protective enzyme Sirtuin]. Gräfe-und-Unzer-Verlag, 127 pages.